RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database

BMC Genomics

Table 6 Tissue/organ-specific miRNAs conserved between rat and human

Tissue/Organ	Expression Type	miRNA	Lilly Rat TSI	NIEHS Rat TSI	Maastricht Rat TSI	Human TSI (body 1/body 2)
Liver	TS	rno-miR-122-3p	1.00	0.97	0.97	1/0.91
Liver	TS	rno-miR-122-5p	1.00	0.97	0.97	0.99/0.94
Heart	OS	rno-miR-208a-3p	1.00	0.98	0.96	0.98/0.96
Pancreas	TS	rno-miR-216a-5p	1.00	0.97	0.96	0.9/0.92
Pancreas	TS	rno-miR-216b-5p	0.99	0.96	0.96	0.72/0.95
Pancreas	TS	rno-miR-217-3p	0.99	0.96	0.96	0.92/0.96
Pancreas	TS	rno-miR-217-5p	0.99	0.97	0.96	0.92/0.96
Intestine^a	OS	rno-miR-215-5p	0.94	–	0.94	–
Testis^b	TS	rno-miR-509-3p	0.99	0.95	0.99	0.96/0.96
Testis^b	TS	rno-miR-509-5p	0.99	0.95	0.98	0.98/0.98
Several	Ubiquitous	rno-miR-21-3p	0.57	0.71	0.71	0.8/0.69

TS tissue-specific, TSI Tissue Specificity Index, OS organ-specific. Specificity determined by RATEmiRs analysis in a one vs all other tissues and using the default parameters for each
Shown are the rat miRNAs that have specific expression and overlap with specific expression of human miRNA from the Human Tissue Atlas
^aIndicates that the miRNA was not an annotated feature in the NIEHS pipeline
^bDenotes that the NIEHS pipeline did not detect the miRNAs as specific
RATEmiRs TSI computed from TMM data and the human TSI computed from the Human Tissue Atlas quantile normalized data

ISSN: 1471-2164