Table 4 Examples of substrate annotation ranking
From: Combining multiple functional annotation tools increases coverage of metabolic annotation
Rank | Substrate | Examples |
|---|---|---|
1 | Metabolite that can be incorporated as a transport reaction in a metabolic model | • Fe • lysine |
2 | Substrate(s) that map to a small number of possible transport reactions | • Mg/Co/Ni • aromatic amino acid |
3 | Broader substrate classes not directly usable to construct a metabolic network | • dipeptide • sugar |
4 | Very broad class of substrates | • multidrug efflux • protein |
5 | No substrate annotated | Â |