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Table 2 Gene ontology analysis of the genes closest to heart-selective lncRNAs

From: Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs

Term

Count

%

p-value

GO:0045944~positive regulation of transcription from RNA polymerase II promoter

40

9.70

2.26E-09

GO:0007507~heart development

19

4.61

1.97E-08

GO:0000122~negative regulation of transcription from RNA polymerase II promoter

31

7.52

6.80E-08

GO:0051891~positive regulation of cardioblast differentiation

5

6.55

1.65E-07

GO:0003151~outflow tract morphogenesis

8

1.94

8.14E-06

GO:0060413~atrial septum morphogenesis

5

1.21

3.01E-05

GO:0060347~heart trabecula formation

5

1.21

4.06E-05

  1. Genes associated with heart development are strongly enriched among genes closest to lncRNAs that are selectively expressed in the heart. Similar terms were omitted