Table 1 P. falciparum genes in the top quartile of expression showing a difference in schizont stage transcript levels between long-term laboratory-adapted clones and recent clinical isolates in culture
Gene ID | Product annotation | Log2 fold difference | Wald test |
|---|---|---|---|
Higher transcription in long-term laboratory-adapted clones | |||
 PF3D7_0422900 | methyltransferase, putative | −2.50 | −6.48 |
 PF3D7_0501300 | skeleton-binding protein 1 | −2.50 | −4.98 |
 PF3D7_0410000 | erythrocyte vesicle protein 1 | −2.38 | −10.62 |
 PF3D7_0104300 | ubiquitin carboxyl-terminal hydrolase 1, putative | −2.18 | −6.13 |
 PF3D7_0522300 | 18S rRNA (guanine-N(7))-methyltransferase, putative | −2.15 | −8.67 |
 PF3D7_0420300 | AP2 domain transcription factor, putative | −2.02 | −7.19 |
 PF3D7_1030200 | claudin-like apicomplexan microneme protein, putative | −2.00 | −9.21 |
 PF3D7_1327300 | conserved Plasmodium protein, unknown function | −2.00 | −4.97 |
Higher transcription in clinical isolates | |||
 PF3D7_1036300 | duffy binding-like merozoite surface protein 2 | 3.02 | 5.32 |
 PF3D7_1302100 | gamete antigen 27/25 | 2.02 | 3.99 |