Fig. 4

Enriched GO terms within the highly variable genes among CL-SL and VL-SL isolates. GO terms found to be overrepresented with a p < 0.05 are shown for biological processes in VL-SL (Panel a) and CL-SL (Panel b). A web-based tool, REVIGO was used to remove redundant GO terms among the gene set based on a chosen semantic similarity measure of 0.5. Remaining GO terms were represented as circles in a two dimensional scatter plot, where the size of the circles indicates the frequency of the GO term it represents and the distance between the circles indicates the semantic similarity between the corresponding GO terms. Circles closer to each other in the plot represent semantically similar GO terms. Circle color indicates the enriched GO term p-values according to the color key given in the plot. Number within each circle corresponds to the GO term as per Additional file 1: Table S9. Plot axes x and y is a general representative measure of semantic space