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Table 1 Genes with highly variable copy numbers between Sri Lankan L. donovani CL-SL and VL-SL isolates

From: Genomic insights into virulence mechanisms of Leishmania donovani: evidence from an atypical strain

Chr

GeneID

VL/CL Ratio

MWU-test p-value

Benjamini-Hochberg p-value

Product Description

27

LdBPK_271940

7.96

0.2717

0.3702

D-Lactate Dehydrogenase-Like Protein

27

LdBPK_271950

6.84

0.0012

0.0029

Branched-Chain Amino Acid Aminotransferase, Putative (Fragment)

10

LdBPK_100520

4.698

0.0000

0.0000

Gp63, Leishmanolysin

29

LdBPK_291600

4.41

0.0000

0.0000

Nodulin-Like, Putative

23

LdBPK_230360

4.22

0.0000

0.0000

Hypothetical Protein, Conserved

23

LdBPK_230350

3.86

0.0022

0.0050

Hypothetical Protein, Conserved

23

LdBPK_230330

3.85

0.0133

0.0264

Checkpoint Protein Hus1, Putative

25

LdBPK_210020

3.80

0.0009

0.0023

Histone H4

10

LdBPK_100920

3.55

0.8462

0.8817

Histone H3

23

LdBPK_230340

3.47

0.0001

0.0004

Tryptophanyl-Trna Synthetase, Putative

23

LdBPK_230320

3.06

0.2234

0.3163

Zinc Finger, C3Hc4 Type (Ring Finger), Putative

23

LdBPK_230310

3.02

0.7210

0.7877

Pteridine Reductase 1

11

LdBPK_110640

2.95

0.0922

0.1456

Metallo-Peptidase, Clan Mf, Family M17 (Fragment)

29

LdBPK_291590

2.90

0.3598

0.4576

Asparagine Synthase, Putative

10

LdBPK_100510

2.55

0.2285

0.3201

Gp63, Leishmanolysin (Fragment)

23

LdBPK_230290*

2.49

0.8027

0.8474

Abc-Thiol Transporter (Fragment)

23

LdBPK_230300

2.47

0.8735

0.9026

Argininosuccinate Synthase, Putative

23

LdBPK_230250*

2.47

0.0540

0.0905

Hypothetical Protein, Conserved

35

LdBPK_353690

2.38

0.0001

0.0003

Hypothetical Protein, Conserved

22

LdBPK_221370

2.36

0.0350

0.0616

40S Ribosomal Protein L14, Putative

31

LdBPK_310470

2.28

0.6628

0.7405

Hypothetical Protein

23

LdBPK_230370

2.27

0.0000

0.0000

Hypothetical Protein, Conserved

23

LdBPK_230260*

2.22

0.1946

0.2790

Hypothetical Protein, Conserved

25

LdBPK_020010

2.20

0.1855

0.2691

Aminopeptidase P1, Putative

15

LdBPK_150430

2.19

0.9484

0.9561

60S Acidic Ribosomal Protein, Putative

27

LdBPK_271490

2.13

0.1280

0.1947

Hypothetical Protein, Conserved

11

LdBPK_111070

2.13

0.3303

0.4289

Hypothetical Protein

28

LdBPK_282050

2.12

0.4786

0.5652

Zinc Transporter 3, Putative

34

LdBPK_341720

2.10

0.9113

0.9300

Amastin-Like Surface Protein, Putative (Fragment)

  1. Benjamini-Hochberg critical value for a false discovery rate < 0.05 was considered significant and marked in bold
  2. *Genes previously reported with high copy number variations between a cutaneous and a visceral isolate from Sri Lanka [14]
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BMC Genomics

ISSN: 1471-2164

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