Skip to main content
Fig. 1 | BMC Genomics

Fig. 1

From: Reveal cell type-specific regulatory elements and their characterized histone code classes via a hidden Markov model

Fig. 1

Illustration of the workflow of CsreHMM. a Transform the binary peak matrix to the specificity matrix for each mark. b Apply HMM to the feature matrix formed by stacking all specificity matrices of all marks to learn specific states. c The emission matrix of trained HMM model. For each state, the specific cell-mark combination is marked by ‘*’. Only state with at least one specific cell-mark combination was defined as a specific state (marked by a colored circle). d A specific cell-mark combination is defined as the one with emission probability above both p0 and ps (explained in Methods)

Back to article page