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Table 5 KEGG pathway annotation of the miRNA potential targets

From: Characterization of miRNA profiles in the mammary tissue of dairy cattle in response to heat stress

Pathway ID

Pathway name

Target genes with pathway annotation (51813)

All genes of the Bos taurus with pathway annotation (55072)

P value

ko04510

Focal adhesion

1593 (3.07%)

1628 (2.96%)

9.23E −14

ko04810

Regulation of actin cytoskeleton

2166 (4.18%)

2218 (4.03%)

2.16E −16

ko04530

Tight junction

2000 (3.86%)

2027 (3.68%)

3.23E −26

ko00500

Starch and sucrose metabolism

221 (0.43%)

222 (0.4%)

1.92E −05

ko01110

Biosynthesis of secondary metabolites

1043 (2.01%)

1084 (1.97%)

9.24E −04

ko04670

Leukocyte transendothelial migration

858 (1.66%)

875 (1.59%)

7.30E −09

ko04350

TGF-beta signaling pathway

367 (0.71%)

377 (0.68%)

2.31E-03

ko04310

Wnt signaling pathway

855 (1.65%)

892 (1.62%)

1.14E-02

ko04330

Notch signaling pathway

299 (0.58%)

310 (0.56%)

4.19E-02

ko04150

mTOR signaling pathway

315 (0.61%)

326 (0.59%)

2.64E-02

ko04011

MAPK signaling pathway - yeast

118 (0.23%)

120 (0.22%)

2.43E-02

ko04630

JAK-STAT signaling pathway

633 (1.22%)

656 (1.19%)

3.33E-03

ko04012

ErbB signaling pathway

505 (0.97%)

519 (0.94%)

4.38E-04

  1. Target genes with pathway annotation, The number of target genes which are associated with the pathway (ratio). All genes of the bos taurus with pathway annotation, The number of all reference genes which are associated with the pathway (ratio)