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Fig. 5 | BMC Genomics

Fig. 5

From: Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming

Fig. 5

Chromatin state transitions, motif usages and their contributions in the maintaining of syntenic conserved peaks. a Chromatin state transitions of syntenic conserved peaks between human and mouse. The top left is state 1 of human to state 1 of mouse. The value in the heatmap represents the fraction of the number of syntenic conserved peaks in that square divided by the total number of all syntenic conserved peaks. b Chromatin state transitions of the log2 ratio between syntenic conserved peaks versus syntenic unconserved peaks. The value in the heatmap represents the log2 ratio between the fraction of syntenic conserved peaks and the fraction of syntenic unconserved peaks in that square. c Percentage of SC, SU and UN peaks that have canonical motifs. d ROC AUC of a classifier to predict syntenic based on motif occurrences and chromatin state transitions

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BMC Genomics

ISSN: 1471-2164

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