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Fig. 7 | BMC Genomics

Fig. 7

From: A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice

Fig. 7

a High-fat (HF) diet mice had significantly higher methylation and higher Adam11 expression than low-fat (LF) diet mice. b HF mice also had higher Galnt10 gene expression, with HF females having significantly less methylation in their first intron than LF females. c HF mice had higher expression of Lad1, and the first intron (also a promoter region) had lower methylation in HF females than LF females. d HF mice had higher expression of the Col1a1 gene than LF mice, with significantly increased methylation in HF males across exons 23 and 24 compared to LF males. e HF males had less methylation at a region between the genes Abcg8 and Abcg5, which lie head-to-head, and the HF males had significantly increased expression of both Abcg8 and Abcg5

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