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Table 1 The distribution of significant differentially methylated regions (DMRs) (q < 0.01) across the genome associated with diet. Numbers indicate how many 500 base pair windows overlap each genomic region, with the percent of the total significant DMRs that overlap such regions in parentheses for the female and male mice. The percent of windows across the entire genome that overlap these genomic regions is listed as a comparison, illustrating the overrepresentation of regulatory regions in the DMRs

From: A high-fat diet alters genome-wide DNA methylation and gene expression in SM/J mice

Region Female DMRs Male DMRs Whole Genome
Enhancer 237 (10.0%) 180 (11.7%) 3.5%
CTCF Binding Site 157 (6.7%) 55 (3.6%) 1.7%
TF binding site 33 (1.4%) 12 (0.8%) 0.3%
Promoter Flanking Region 795 (33.8%) 522 (33.9%) 8.1%
Promoter 370 (15.7%) 215 (14.0%) 4.5%
Exon 598 (25.4%) 415 (27.0%) 7.5%
Intergenic 748 (31.8%) 471 (30.6%) 58.6%