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Table 2 Agreement measure λ>0.7 for the benchmarking of BRAINEAC against GTEx across 4 brain regions in 287 KEGG pathways

From: A measure of agreement across numerous conditions: assessing when changes in network structures are tissue-specific

λ

CI: 2.5%

CI: 97.5%

σ

Ref

Description

0.97

0.99

1.00

0.01

hsa04724

Glutamatergic synapse

0.95

0.97

1.00

0.01

hsa05033

Nicotine addiction

0.94

0.93

1.00

0.01

hsa04360

Axon guidance

0.91

0.93

1.00

0.02

hsa05414

Dilated cardiomyopathy

0.89

0.97

1.00

0.02

hsa04931

Insulin resistance

0.84

0.88

0.99

0.03

hsa04725

Cholinergic synapse

0.84

0.82

0.97

0.02

hsa05032

Morphine addiction

0.82

0.78

0.93

0.02

hsa04720

Long-term potentiation

0.82

0.76

0.89

0.02

hsa05031

Amphetamine addiction

0.81

0.76

0.95

0.02

hsa04912

GnRH signaling pathway

0.79

0.70

0.91

0.03

hsa04261

Adrenergic signaling in cardiomyocytes

0.76

0.75

0.78

0.01

hsa04727

GABAergic synapse

0.75

0.75

0.75

0.00

hsa04080

Neuroactive ligand-receptor interaction

0.75

0.75

0.75

0.00

hsa04723

Retrograde endocannabinoid signaling

0.74

0.75

0.75

0.00

hsa04020

Calcium signaling pathway

0.74

0.73

0.76

0.01

hsa04728

Dopaminergic synapse

0.74

0.76

0.90

0.03

hsa05206

MicroRNAs in cancer

0.73

0.75

0.76

0.01

hsa04015

Rap1 signaling pathway

0.71

0.67

0.95

0.04

hsa04971

Gastric acid secretion

0.71

0.68

0.80

0.02

hsa05034

Alcoholism