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Fig. 1 | BMC Genomics

Fig. 1

From: Genome rearrangements in Escherichia coli during de novo acquisition of resistance to a single antibiotic or two antibiotics successively

Fig. 1

Experimental scheme. Wild-type E. coli MG1655 was exposed to stepwise increasing concentrations of amoxicillin (AMX), enrofloxacin (ENRO), kanamycin (KAN), or tetracycline (TET), resulting in strains with a de novo acquired resistance to a single antibiotic. The resistant strains were subsequently made resistant to the three other antibiotics. Each induction of resistance was performed in duplicate, resulting in four replicates with an identical exposure history of the double resistant strains

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