Fig. 5

Construction of the coexpression network. a Correlation coefficients between each group and the gene expression in the module. The x-axis and y-axis represented the group and the module, respectively. The secondary KEGG categories that most significantly enriched pathways belonged to were labeled in the parentheses under module names. The grey module contained genes that were unable to classify into any other modules, therefore, the enrichment analysis was not conducted in genes of the grey module. The red and green colors indicated the highest positive and negative correlation between sample groups and modules. The correlation coefficient (1st line) and p-value (2nd line) were labeled. NRSFB: 3 samples of female brain in NRS; NRSFG: 3 samples of female gonad in NRS; NRSMB: 3 samples of male brain in NRS; NRSMG: 3 samples of male gonad in NRS; RSFB: 3 samples of female brain in RS; RSFG: 3 samples of female gonad in RS; RSMB: 3 samples of male brain in RS; RSMG: 3 samples of male gonad in RS. b KEGG functional enrichment of genes in the darkgreen and theh royalblue modules. c Network of genes in the darkgreen module with weight greater than 0.25. The node and edge represent the gene and weight between two genes. The red and green colors of the nodes indicated the high and low connectivity to other nodes. The larger node size also denoted the higher connectivity as well. The hub genes were labeled in red