Table 2 Twenty-four top differentially expressed genes and their functions

CXCL8 IL8

C-X-C motif chemokine ligand 8

Participates in the immune response, cellular response to tumor necrosis factor, regulation of cell proliferation and cell cycle arrest

ISG15

ISG15 ubiquitin-like modifier

Plays a key role in the innate immune response to viral infection, ubiquitination and apoptosis

IL33

Interleukin 33

Participates in the response to viral infection, regulation of cell proliferation and RNA transcription, ubiquitination and apoptosis

FABP4

Fatty acid binding protein 4

Involved in cell cycle, cell differentiation, positive regulation of cell proliferation and positive regulation of inflammatory response

PLAUR

Plasminogen activator, urokinase receptor

Plays a role in positive regulation of epidermal growth factor and involved in the apoptosis

HMOX1

Heme oxygenase 1

Positive regulation of apoptotic process, regulation of transcription and cell proliferation

CTNNBIP1

Catenin beta interacting protein 1

Involved in cell cycle, cell proliferation, regulation of transcription and regulation of inflammatory response

CXCL2

chemokine (C-X-C motif) ligand 2

Plays role in the immune response and cell proliferation

YOD1

YOD1 deubiquitinase

Plays a role in the ubiquitin pathway

RNF19B

Ring finger protein 19B

Plays a role in the ubiquitin pathway

UBA7

Ubiquitin like modifier activating enzyme 7

Plays a role in the ubiquitin pathway

S100A9

S100 calcium binding protein A9

Involved in the immune response, regulation of inflammatory response and apoptosis

S100A8

S100 calcium binding protein A8

Involved in the immune response, regulation of inflammatory response and apoptosis

CASP14

Caspase 14

Plays a role in the apoptosis

BNIP3

BCL2 interacting protein 3

Participates in defense response to virus, and negative regulation of apoptotic process

TMEM79

Transmembrane protein 79

Structural molecule activity

TERT

Telomerase reverse transcriptase

Involved in cell cycle, regulation of transcription and structural molecule activity

HEYL

Hes related family bHLH transcription factor with YRPW motif-like

Involved in cell differentiation

JUNB

JunB proto-oncogene, AP-1 transcription factor subunit

Participates in cell proliferation, cell cycle and regulation of transcription

CSRP2

Cysteine and glycine rich protein 2

Involved in cell differentiation

CTNNBIP1

Catenin beta interacting protein 1

Cell proliferation and differentiation, involved in acute inflammatory response and regulation of transcription

NME2

non-metastatic cells 2, protein (NM23B) expressed in

Regulation of apoptotic process and transcription

ALOX12B

Arachidonate 12-lipoxygenase, 12R type

Regulation of transcription

CHP2

Calcineurin like EF-hand protein 2

Participates of cell proliferation and regulation of transcription