Fig. 3

Distribution plot and test accuracy. a Shown are distribution plots of pairwise correlation coefficients in 934 RNA-seq (light blue), 326 WES datasets (dark blue), and correlations between RNA-seq and WES data. The estimated normal distribution is also plotted in black line; and (b) Mean correlation coefficients (of 6 replicate pairs highlighted in brown color in Fig. 2a) obtained for the best match and the second best match using all variants, COSMIC70 and COSMIC83 constrained variants, RNAseq-WES variants and randomly permuted mutation positions