Fig. 6
From: Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics
Trait-trait association network based on Fisher’s Exact Test. a Network obtained using adjusted pFET < 1 × 10− 3. b Network obtained using adjusted pFET < 0.01. Each node represents a trait. Node color indicates trait group (purple: neurological/neuropsychiatric traits, orange: anthropometric and social traits, blue: immune-related traits, and green: metabolic traits). Edge indicates the two end traits shared a significant number of pathways. Edge width is proportional to the -log10-transformed adjusted pFET. Edge labels represent the number of shared associated pathways. (C) The number of pathways significantly associated with each trait (pcombined < 0.01)