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Fig. 5 | BMC Genomics

Fig. 5

From: CpG traffic lights are markers of regulatory regions in human genome

Fig. 5

CpG TL within transcription factor binding sites. CpG TL to CpG BG ratio vs Fisher’s exact test p-value within a all predicted TFBS; b TFBS and 50 nt shores for CpG TL with a negative SCC and c the same for CpG TL with a positive SCC. Length-normalized distribution of CpG TL / CpG BG counts (negative SCC) within TFBS and 100 nt shores: d NRF1; f SPIB; h STAT1; j GABPA; m IRF4. Per position distribution of CpG TL / CpG BG counts (negative SCC) within TFBS with logo: e NRF1; g SPIB; i STAT1; k GABPA; n IRF4. In vitro binding preferences of unmethylated and methylated oligos: l GABPA; o IRF4

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