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Table 4 Overrepresented Nervous System Related GO Terms Associated with Week 3 Downregulated Genes

From: Chronic circadian misalignment results in reduced longevity and large-scale changes in gene expression in Drosophila

GO ID GO Term Adjusted p-Value Number of Genes Fold Enrichment
GO:0007399 nervous system development 2.15E-21 72 3.9
GO:0022008 neurogenesis 1.51E-19 62 4.2
GO:0061564 axon development 9.25E-11 30 5.3
GO:0050808 synapse organization 1.13E-06 23 4.7
GO:0007611 learning or memory 3.34E-06 17 6.2
GO:0050890 cognition 3.34E-06 17 6.2
GO:0007420 brain development 1.27E-04 13 6.6
GO:0040040 thermosensory behavior 6.09E-04 6 19.3
GO:0007416 synapse assembly 1.61E-03 14 4.9
GO:0045475 locomotor rhythm 4.24E-03 9 7.6
GO:0007417 central nervous system development 5.05E-03 17 3.7
GO:0007268 chemical synaptic transmission 1.34E-02 17 3.5
  1. Adjusted p-value is based on Bonferroni correction. Number of genes refers to genes annotated with that term out of the 245 week 3 downregulated genes. Fold enrichment is compared to the relative prevalence of genes annotated with the term in the full set of Drosophila coding genes.