Fig. 7
From: RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress
Conservation of age-related translational and transcriptional changes between oenocytes and liver. a Venn diagram comparing genes/proteins differentially expressed in aged human liver and aged fly oenocytes. GO terms for age-regulated proteins in human liver were shown in the lower panel. b Venn diagram comparing genes differentially expressed in aged mouse liver and aged fly oenocytes. GO terms for age-regulated genes in mouse liver were shown in the lower panel. OXPHOS: oxidative phosphorylation. c and d List of all genes in Ras/MAPK signaling pathway that were down-regulated in aged fly oenocytes and mouse liver. Protein network was generated using STRING (with kmeans clustering option). Continuum edge indicates a high confidence score. Dashed edge indicates a low confidence score