Fig. 3

Accuracy and specificity on lncRNA and pri-miRNA promoters. Top: Model specificity on promoters of lncRNA (a) and pri-miRNAs (b). These figures represent the distribution of AUC differences obtained when using a model learned on a first ChIP-seq experiment to predict the outcome of a second ChIP-seq experiment. Different pairs of ChIP-seq experiments were used: experiments on the same TF and same cell type (red), experiments on the same TF but different cell types (yellow), experiments on different TFs but same cell type (light blue), and experiments on different TFs and different cell types (blue). For each pair of ChIP-seq experiment A-B, we measured the difference between the AUC achieved on A using the model learned on A, and the AUC achieved on A using the model learned on B. AUC differences were measured on the expression-controlled case. Bottom: Promoter models are interchangeable. For each ChIP-seq experiment, we computed the AUC of the model learned and applied on mRNAs (pink), learned and applied on lncRNAs (yellow-green), learned and applied on pri-miRNAs (blue), learned on mRNAs and applied to lncRNAs (green), learned on mRNAs and applied to pri-miRNAs (purple)