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Fig. 4 | BMC Genomics

Fig. 4

From: RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia

Fig. 4

Distinct components of the CSE and replicative senescence expression response. a Hierarchical clustering of genes with the top 50 most stable expression changes between control, CSE-exposed, and senescent condition. Relative expression levels per gene are shown, from low (blue) to high (red). b Principal component analysis of clustering in conditions using genes in a). Ternary plot shows positions along three PC axes in each condition. c Enrichments among chIP-seq genomic targets of transcription factors (ChEA; upper panel) and biological pathways (Wikipathways; lower panel) in stably switching genes

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