Skip to main content

Table 2 Ranking of the top 10 upregulated and downregulated differentially expressed genes in the CpG DNA dataset. Ranking based on fold change

From: Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line

Gene ID Name Fold change p value FDR
A
TNFSF18 768,081 tumor necrosis factor superfamily member 18 5.3 6.9 × 10−4 2.4 × 10− 2
Slc26a10 506,076 solute carrier family 26 member 10 4.3 1.2 × 10−3 3.5 × 10− 2
NR4A1 528,390 nuclear receptor subfamily 4 group A member 1, transcript variant X3 3.1 9.7 × 10−5 6.2 × 10− 3
IGFLR1 617,594 IGF like family receptor 1 3.1 6.6 × 10−5 4.7 × 10−3
GSDMB 509,296 gasdermin B 2.5 6.4 × 10−5 4.6 × 10−3
LBH 616,148 limb bud and heart development 2.2 6.7 × 10−14 4.6 × 10− 10
LY6G5B 539,236 lymphocyte antigen 6 complex, locus G5B 2.2 1.4 × 10−3 3.9 × 10− 2
MYOZ2 540,487 myozenin 2, transcript variant X1 2.7 4.01 × 10−5 3.5 × 10−3
RRAD 505,165 Ras-related associated with diabetes 2.0 5.8 × 10−5 4.3 × 10−3
PLAU 281,983 plasminogen activator, urokinase receptor 1.7 4.6 × 10−8 2.1 × 10−5
B
CYP1A1 282,870 cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1, transcript variant X2 −2.8 4.3 × 10−10 6.6 × 10−7
CYP1B1 511,470 cytochrome P450, family 1, subfamily B, polypeptide 1 −2.4 2.0 × 10− 10 4.0 × 10−7
ID1 497,011 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein −2.4 3.5 × 10− 16 4.9 × 10− 12
GPR35 505,056 G protein-coupled receptor 35, transcript variant X7 − 2.4 2.4 × 10−4 1.2 × 10− 2
SLC25A34 515,553 solute carrier family 25 member 34 − 2.3 2.3 × 10−5 2.4 × 10− 3
EDN2 319,094 endothelin 2, transcript variant X1 − 2.1 3.4 × 10−8 1.7 × 10−5
ATOH8 616,225 atonal bHLH transcription factor 8, transcript variant X1 −2.1 5.1 × 10− 9 4.4 × 10− 6
ID3 538,690 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein −2.0 1.2 × 10− 12 5.8 × 10− 9
BDKRB1 532,119 bradykinin receptor B1 −1.9 1.1 × 10−4 6.7 × 10− 3
  1. (A) upregulated, (B) downregulated. Data were analyzed in IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis