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Table 3 Top 20 genes undergoing positive selection in D. aldrichi. Orthogroups with Bonferroni corrected p-value < 1.0e− 20 and Likelihood ratio test statistic estimate from aBSREL > 82. Functional information for each gene was summarised based on Flybase descriptions for D. melanogaster orthologues, classification of the protein sequence using gene ontology and/or Pfam family annotations. Asterisks indicate two genes which also have inparalogues in the D. aldrichi branch

From: Genomic changes associated with adaptation to arid environments in cactophilic Drosophila species

D. aldrichi gene D. melanogaster orthologue Gene name Gene function
DALD015788* FBgn0001341 lethal (1) 1Bi (l(1)1Bi) Transcriptional regulator during larval and embryo stages
DALD015521 FBgn0034583 CG10527 DUF3421; Farnesoic acid O-methyl transferase
DALD011516 FBgn0034031 CG12963 NA
DALD011555 FBgn0029518 CG13376 NA
DALD014639 FBgn0038654 CG14298 Serine-type endopeptidase inhibitor activity
DALD008141 FBgn0037244 CG14647 Transcriptional regulator of protein homo-oligomerisation
DALD001586 FBgn0029686 CG2941 NA
DALD015580* FBgn0050440 CG30440 Involved in positive regulation of Rho protein signal transduction
DALD010188 FBgn0266566 CG45105 Centrosome organising gene
DALD004399 FBgn0038921 CG6332 Testicular haploid expressed repeat
DALD000608 FBgn0036179 CG7368 Transcription factor regulating phagocytosis
DALD007329 FBgn0045495 Gustatory receptor 28b (Gr28b) Taste receptor involved in perception of chemical stimuli
DALD007082 FBgn0032416 Gustatory receptor 33a (Gr33a) Taste receptor involved in perception of chemical stimuli and courtship behaviour
DALD009511 FBgn0031275 metabotropic GABA-B receptor subtype 3 (GABA-B-R3) G-protein coupled receptor regulating glucose metabolic processes
DALD010061 FBgn0051025 Protein phosphatase 1c interacting protein 1 (Ppi1) DUF4788, involved in protein phosphatase binding
DALD012340 FBgn0003460 sine oculis (so) Homeobox gene regulating circadian rhythm, reproduction and development
DALD002312 FBgn0260861 TRAPP subunit 23 (Trs23) Trafficking protein involved in vesicle-mediated transport
DALD007827 FBgn0033055 Tubulin-specific chaperone E (Tbce) Regulates neurogenesis and neuromuscular synaptic transmission
DALD005587 FBgn0085362 Vitellin membrane-like (Vml) vitellin membrane formation and dorsal/ventral axis specification
DALD009987 FBgn0015569 α-Esterase10 (α-Est10) Regulator of imaginal disc-derived wing morphogenesis