Table 2 Differential expression results of the three comparisons. Only detections by both programs are showed and for the selection, the adjusted p values of each program were used. Log2 FC of 7.000 in DESeq2 means that the miRNA was present in one group of samples but not in the other
From: Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq
miRNA Name | DESeq2 | EdgeR | ||
|---|---|---|---|---|
Log2FC | Padj | Log2FC | FDR | |
Lesions-Seronegative | ||||
oar-mir-322-3p | −2.830 | 0.003 | −2.880 | 0.005 |
chi-miR-30f-5p | −2.199 | 0.0001 | −2.226 | 0.02 |
oar-mir-361-3p | 7.000 | 5.64E-13 | 14.182 | 3.1E-09 |
oar-mir-361-5p | 7.000 | 4.57E-17 | 13.137 | 3.11E-08 |
chi-miR-449a-5p | 6.270 | 0.017 | 6.105 | 0.009 |
mmu-let-7e-3p | −2.092 | 0.029 | −2.149 | 0.008 |
mmu-miR-144-3p | 2.824 | 0.002 | 2.792 | 0.0007 |
oar-mir-32-5p | 3.939 | 3.45E-05 | 3.877 | 0.0001 |
oar-mir-340-5p | 1.827 | 0.029 | 1.746 | 0.038 |
oar-mir-34-nvb-5p | 1.575 | 0.002 | 1.500 | 0.003 |
bta-miR-142-5p | 7.000 | 3E-10 | 12.956 | 3.79E-05 |
oar-mir-9/mir-79-nv1-5p | 4.173 | 0.0002 | 4.045 | 0.043 |
chi-mir-92a-3p | −1.559 | 0.0002 | − 1.609 | 0.008 |
oar-mir-36-f-3p | 7.000 | 2.84E-09 | −14.383 | 3.84E-06 |
ssc-mir-7134-3p | −3.517 | 0.0005 | −3.676 | 0.009 |
ssc-mir-7134-5p | −3.967 | 0.0002 | − 3.968 | 4.45E-05 |
oar-let-7b | −1.458 | 5.28E-05 | −1.519 | 0.002 |
oar-let-7f | 1.156 | 0.003 | 1.078 | 0.003 |
oar-miR-125b | −2.083 | 2.65E-08 | −2.134 | 3.84E-06 |
oar-miR-134-5p | 3.267 | 0.026 | 3.184 | 0.002 |
oar-miR-136 | 2.623 | 0.047 | 2.529 | 0.003 |
oar-miR-148a | 1.579 | 2E-05 | 1.501 | 1.93E-06 |
oar-miR-181a | −1.781 | 1.16E-05 | −1.836 | 6.47E-05 |
oar-miR-200a | 1.614 | 0.001 | 1.533 | 0.008 |
oar-miR-21 | 3.584 | 2E-05 | 3.500 | 8.64E-16 |
oar-miR-299-3p | 2.910 | 0.025 | 2.726 | 0.008 |
oar-miR-29b | 2.156 | 0.01 | 2.087 | 0.016 |
oar-miR-30c | −1.440 | 0.0002 | −1.486 | 0.003 |
oar-miR-369-3p | 2.966 | 0.043 | 2.858 | 0.002 |
oar-miR-376c-3p | 2.268 | 0.022 | 2.158 | 0.002 |
oar-miR-376e-3p | 2.058 | 0.032 | 1.975 | 0.006 |
oar-miR-379-5p | 2.336 | 0.017 | 2.237 | 0.008 |
oar-miR-411a-5p | 2.181 | 0.008 | 2.084 | 0.026 |
oar-miR-99a | −1.117 | 0.002 | −1.168 | 0.025 |
Seropositive asymptomatic-Seronegative | ||||
oar-mir-361-3p | 7.000 | 7.11E-10 | 11.903 | 5.25E-07 |
oar-mir-361-5p | 7.000 | 2.08E-17 | 13.286 | 6.77E-08 |
mmu-miR-144-3p | 3.733 | 6.95E-05 | 3.690 | 8.51E-06 |
oar-mir-32-5p | 3.679 | 0.0002 | 3.634 | 0.0005 |
bta-miR-142-5p | 7.000 | 2.42E-11 | 13.831 | 1.67E-05 |
mmu-miR-98-5p | 5.023 | 0.0002 | 5.006 | 0.029 |
oar-let-7f | 1.303 | 0.0007 | 1.237 | 0.0005 |
oar-miR-125b | −1.361 | 0.0007 | −1.401 | 0.008 |
oar-miR-148a | 1.297 | 0.0009 | 1.224 | 0.0002 |
oar-miR-21 | 2.099 | 0.026 | 2.029 | 5.99E-06 |
Lesions-Seropositive asymptomatic | ||||
oar-mir-148/mir-152-5p | −4.143 | 0.032 | −4.098 | 0.005 |
oar-mir-36-f-3p | 7.000 | 6.99E-08 | −13.615 | 6.42E-05 |
ssc-mir-7134-5p | −3.016 | 0.044 | −2.973 | 0.009 |