Fig. 6

STRING pathway analyses diagram for transcripts upregulated in females. Based on the elevated transcripts, several pathways are affected in females. Examples include nucleotide, purine ribonucleoside, ribonucleotide, carbohydrate derivative, heterocyclic, zinc ion, ATP, transitional metal ion, cytoskeletal protein, GABA receptor binding pathways, hydrolase, nucleoside triphosphate, ATPase, L-amino acid transmembrane transporter, and palmitoyl-CoA 9-desaturase activity. Network nodes represent proteins. Splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus. Node colors are arbitrary. Edges represent protein-protein associations. Associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other. Edge confidence is the relative amount of supporting evidence for the connection between two proteins in the diagram. Thicker lines have more support; thinner lines have less support