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Table 1 Chromosomes with lower than average numbers of housekeeping genes are predisposed to become sex chromosomes

From: Dosage sensitivity of X-linked genes in human embryonic single cells

Chromosome No. of housekeeping genes with one-to-one orthologs No. of all genes with one-to-one orthologs P value
(Chi-squared Test)
chicken chr1/4 other chicken autosomes chicken chr1/4 other chicken autosomes
Complete chromosomes
 Chicken chr1 316 2384 1615 9840 <  10−4
 Chicken chr4 160 2540 835 10,620 0.002
Syntenic regions
 Chicken chr1 205 2495 1065 10,390 0.0006
 Chicken chr4 149 2551 802 10,653 0.0006