Fig. 1

CRISPR-Cas type I-F systems in Vibrio cholerae. a A canonical type I-F system present within VPI-6 in V. cholerae strain HC36A1 at the same location as VPI-1 in N16961. b Variant type I-FV1 in strain 490–93 contains one additional gene encoding a hypothetical protein (HP). c Type I-FV2 in strain RC385 lacks a cas8 gene and contains variant cas7fv and cas5fv genes. d Type I-FV3 in strain TM 11079–80 contains a transposase (tnp) inserted in cas3, no cas8 homolog is present and contains the variant cas7fv and cas5fv genes. Genomic comparisons and gene arrangements were constructed via Easyfig [74]. Grayscale bars represents nucleotide homology. Black diamonds of CRISPRs represent direct repeats and colored rectangles represent spacers. The core genes are colored in black, transposases in pink and integrases in red. Red brackets indicate the genomic location of CRISPR