Fig. 7

CRISPR-Cas type I-E system present on GI-24. a Type I-E CRISPR-Cas island characterized in classical V. cholerae strains (O395) inserted between VC0289 and VC0290 relative to the El Tor biotype strain N16961 that lacked the island. b These type I-E systems have a conserved PAM of 3’ NTT 5′ and c a canonical type I-E direct repeat. Genomic comparisons were performed using Easyfig and grayscale bars represent nucleotide homology. The core genes are colored in black, transposases are colored in pink and integrases are red. Red brackets indicate the genomic location of CRISPR. (d) CRISPR-Cas island in V. harveyi ATCC 43516, which also contains a type three secretion system (T3SS) and is inserted between LA59_08695 and LA59_08700 relative to V. harveyi ATCC 33843 that lacks the region