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Table 1 TF motifs over-represented in the induced enhancers

From: Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection

TF Motif # overlapping enhancers Expression, TPM log2FC FDR
FOSL1::JUNB 118 (45.9%) 19.4 / 523.7 5.4 / 2.6 2.7e-03 / 1e-04
RBPJ 117 (45.5%) 295.7 1.8 7.3e-03
REL 96 (37.4%) 165.3 3 4.3e-06
FOSL2::JUNB 91 (35.4%) 81.2 / 523.7 2.4 / 2.6 1.2e-06 / 1e-04
IRF1 88 (34.2%) 1099.8 2.8 1.5e-04
RELA 87 (33.9%) 309 1.7 1e-06
JUNB 84 (32.7%) 523.7 2.6 1e-04
FOSL1 80 (31.1%) 19.4 5.4 2.7e-03
FOSL2 80 (31.1%) 81.2 2.4 1.2e-06
Nfe2l2 54 (21%) 684 1.5 2.4e-03
JDP2 53 (20.6%) 67.7 2.9 4.8e-04
NFKB2 28 (10.9%) 496.3 2.7 2.5e-04
  1. Columns show TF motif name, number and percentage of overlapping enhancers among the induced enhancers, average expression of the corresponding TF(s) in infected BMDM at 4 h, fold change and FDR of differentially expressed test for the corresponding TF(s) in infected BMDM at 4 h versus non-infected control at 0 h. Motifs were retained for TFs with significant up-regulation at 4 h