Fig. 1From: A mathematical model as a tool to identify microRNAs with highest impact on transcriptome changesLevels of Renilla luciferase mRNA in control and irradiated Me45 cells. Cells were transfected with a reporter gene plasmid containing a Renilla luciferase gene with the same promoter and coding sequence but whose primary transcript contained target sequences for different miRNAs versus those that did not contain the targets (empty). Renilla mRNA was assayed by RT-PCR and normalized to the Firefly mRNA to exclude differences in transfection efficiency between experiments. Error bars represent standard deviations of values obtained in three experiments, and p-values show the significance of differences between control and irradiated samples tested by a two sample t-testBack to article page