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Table 5 Selected pathways regulated by the 30 highest-ranked miRNAs

From: A mathematical model as a tool to identify microRNAs with highest impact on transcriptome changes

KEGG pathway

p-value

Number of genes

Number of miRNAs

Hippo signaling pathway

0.00003

67

12

Transcriptional misregulation in cancer

0.0003

82

14

Circadian rhythm

0.0022

20

7

Endocytosis

0.0033

93

14

ErbB signaling pathway

0.0048

43

13

TGF-beta signaling pathway

0.0117

38

12

mTOR signaling pathway

0.0117

32

13

Wnt signaling pathway

0.0119

65

13

Hedgehog signaling pathway

0.0242

27

13

FoxO signaling pathway

0.0270

60

10