Fig. 3

The overall architecture of our new SNP detection scheme. This figure depicts the general process of proposed SNP detection scheme. The set of panel sequences noted in yellow and the patient genome sequence noted in blue are chunked down into K-mers, respectively. After we encrypt K-mers, the client-side patient’s encrypted K-mers are transmitted to the server. The black box depicted in the middle denotes the homomorphic evaluation procedure. Here, we check the matching correspondence between any member in panel K-mer set and in the patient K-mer set. The result noted green is returned to the patient. The patient can decrypt the result with the private key securely on the client-side environment