TY - JOUR AU - Boettcher, M. AU - McManus, M. T. PY - 2015 DA - 2015// TI - Choosing the right tool for the job: RNAi, TALEN, or CRISPR JO - Mol Cell VL - 58 UR - https://doi.org/10.1016/j.molcel.2015.04.028 DO - 10.1016/j.molcel.2015.04.028 ID - Boettcher2015 ER - TY - JOUR AU - Doench, J. G. PY - 2018 DA - 2018// TI - Am I ready for CRISPR? A user's guide to genetic screens JO - Nat Rev Genet VL - 19 UR - https://doi.org/10.1038/nrg.2017.97 DO - 10.1038/nrg.2017.97 ID - Doench2018 ER - TY - JOUR AU - Altschuler, S. J. AU - Wu, L. F. PY - 2010 DA - 2010// TI - Cellular heterogeneity: do differences make a difference? JO - Cell VL - 141 UR - https://doi.org/10.1016/j.cell.2010.04.033 DO - 10.1016/j.cell.2010.04.033 ID - Altschuler2010 ER - TY - JOUR AU - Wang, T. PY - 2014 DA - 2014// TI - Genetic screens in human cells using the CRISPR-Cas9 system JO - Science VL - 343 UR - https://doi.org/10.1126/science.1246981 DO - 10.1126/science.1246981 ID - Wang2014 ER - TY - STD TI - Gilbert LA, et al. Genome-scale CRISPR-mediated control of gene repression and activation. Cell. 2014. ID - ref5 ER - TY - JOUR AU - Koike-Yusa, H. PY - 2014 DA - 2014// TI - Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library JO - Nat Biotechnol VL - 32 UR - https://doi.org/10.1038/nbt.2800 DO - 10.1038/nbt.2800 ID - Koike-Yusa2014 ER - TY - JOUR AU - Zhou, Y. PY - 2014 DA - 2014// TI - High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells JO - Nature VL - 509 UR - https://doi.org/10.1038/nature13166 DO - 10.1038/nature13166 ID - Zhou2014 ER - TY - STD TI - Evers B, et al. CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes. Nat Biotechnol. 2016;34(6):631-3. ID - ref8 ER - TY - JOUR AU - Boettcher, M. PY - 2018 DA - 2018// TI - Dual gene activation and knockout screen reveals directional dependencies in genetic networks JO - Nat Biotechnol VL - 36 UR - https://doi.org/10.1038/nbt.4062 DO - 10.1038/nbt.4062 ID - Boettcher2018 ER - TY - JOUR AU - Schmierer, B. PY - 2017 DA - 2017// TI - CRISPR/Cas9 screening using unique molecular identifiers JO - Mol Syst Biol VL - 13 UR - https://doi.org/10.15252/msb.20177834 DO - 10.15252/msb.20177834 ID - Schmierer2017 ER - TY - STD TI - Michlits G, et al. CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens. Nat Methods. 2017. ID - ref11 ER - TY - JOUR AU - Wang, S. PY - 2008 DA - 2008// TI - The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway JO - Oncogene VL - 27 UR - https://doi.org/10.1038/onc.2008.298 DO - 10.1038/onc.2008.298 ID - Wang2008 ER - TY - JOUR AU - Chi, S. AU - Weiss, A. AU - Wang, H. PY - 2016 DA - 2016// TI - A CRISPR-based toolbox for studying T cell signal transduction JO - Biomed Res Int VL - 2016 ID - Chi2016 ER - TY - JOUR AU - Li, W. PY - 2014 DA - 2014// TI - MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens JO - Genome Biol VL - 15 UR - https://doi.org/10.1186/s13059-014-0554-4 DO - 10.1186/s13059-014-0554-4 ID - Li2014 ER - TY - JOUR AU - Hanna, R. E. AU - Doench, J. G. PY - 2018 DA - 2018// TI - A case of mistaken identity JO - Nat Biotechnol VL - 36 UR - https://doi.org/10.1038/nbt.4208 DO - 10.1038/nbt.4208 ID - Hanna2018 ER - TY - JOUR AU - Hegde, M. PY - 2018 DA - 2018// TI - Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens JO - PLoS One VL - 13 UR - https://doi.org/10.1371/journal.pone.0197547 DO - 10.1371/journal.pone.0197547 ID - Hegde2018 ER -