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Fig. 5 | BMC Genomics

Fig. 5

From: Genome analysis identifies a spontaneous nonsense mutation in ppsD leading to attenuation of virulence in laboratory-manipulated Mycobacterium tuberculosis

Fig. 5

Intracellular survival and infectivity of M. tb strains. a Intracellular survival of M. tb strains in THP-1 infection model. Intracellular bacteria were recovered from THP-1 cells by lysis at various time points and bacterial survival was determined by CFU analysis. b Infectivity of M. tb strains in THP-1 cells analyzed after infection. Results are shown as the mean ± SD of 3 independent experiments. [***, pvalue < 0.001 in comparison to H37Rv]

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BMC Genomics

ISSN: 1471-2164

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