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Table 2 The top 30 genes with differential expression reported by the OMICfpp method using an 0.37 and 0.93 orness value, respectively, with the complete distribution

From: OMICfpp: a fuzzy approach for paired RNA-Seq counts

ENSEMBL ID Gene symbol Synonyms CRC status Other cancer
Results using an orness value of 0.37
ENSG00000001497 LAS1L FLJ12525, WTS, Las1-like, dJ475B7.2 New Known [33]
ENSG00000002079 MYH16 MHC20, MYH16P, MYH5 New New
ENSG00000003147 ICA1 ICA69, ICAp69 New Known [34]
ENSG00000005844 ITGAL CD11A; LFA-1; LFA1A Known [40] Known [41]
ENSG00000006071 ABCC8 HI, SUR, HHF1, MRP8, PHHI, SUR1, ABC36, HRINS, TNDM2, SUR1delta2 Known [42] Known [43]
ENSG00000006327 TNFRSF12A FN14, CD266, TWEAKR New Known [35]
ENSG00000006704 GTF2IRD1 BEN, WBS, GTF3, RBAP2, CREAM1, MUSTRD1, WBSCR11, WBSCR12, hMusTRD1alpha1 New known [36]
ENSG00000010539 ZNF200 - New New
ENSG00000011201 ANOS1 HH1, HHA, KAL, KMS, KAL1, ADMLX, WFDC19, KALIG-1 Known [44] Known [45]
ENSG00000013293 SLC7A14 PPP1R142 New New
ENSG00000015285 WAS THC, IMD2, SCNX, THC1, WASP, WASPA Known [46] Known [47]
ENSG00000015592 STMN4 RB3 Known [48] Known [49]
ENSG00000018236 CNTN1 F3, GP135, MYPCN Known [50] Known [51]
ENSG00000018280 SLC11A1 LSH, NRAMP, NRAMP1 Known [30] Known [52]
ENSG00000029559 IBSP BSP, BNSP, SP-II, BSP-II Known [53] Known [53]
ENSG00000030304 MUSK CMS9, FADS Known [54] Known [55]
ENSG00000033122 LRRC7 DENSIN New New
ENSG00000034971 MYOC GPOA, JOAG, TIGR, GLC1A, JOAG1 New Known [38]
ENSG00000036672 USP2 USP9, UBP41 Known [56] Known [57]
ENSG00000040275 SPDL1 CCDC99, FLJ20364, hSpindly New Known [58]
ENSG00000040731 CDH10 - New Known [59]
ENSG00000043143 JADE2 PHF15, JADE-2 New New
ENSG00000044012 GUCA2B - Known [60] New
ENSG00000046774 MAGEC2 CT10, HCA587, MAGEE1 Known [31] Known [31]
ENSG00000047617 ANO2 C12orf3, TMEM16B New New
ENSG00000048462 TNFRSF17 BCM, BCMA, CD269, TNFRSF13A Known [61] Known [62]
ENSG00000050030 NEXMIF XPN, MRX98, KIDLIA, KIAA2022 New New
ENSG00000053524 MCF2L2 ARHGEF22 New New
ENSG00000058600 POLR3E SIN; RPC5 New New
ENSG00000060718 COL11A1 STL2, COLL6, CO11A1 Known [63] Known [64]
Results using an orness value of 0.93
ENSG00000001460 STPG1 MAPO2, C1orf201 New New
ENSG00000001497 LAS1L FLJ12525, WTS, Las1-like, dJ475B7.2 New Known [33]
ENSG00000002822 MAD1L1 MAD1, PIG9, TP53I9, TXBP181 Known [65] Known [66]
ENSG00000003096 KLHL13 BKLHD2 New New
ENSG00000003147 ICA1 ICA69, ICAp69 New Known [34]
ENSG00000003249 DBNDD1 - New New
ENSG00000004487 KDM1A AOF2, BHC110, KDM1, KIAA0601, LSD1 Known [67] Known [68]
ENSG00000004848 ARX SSX, PRTS, CT121, EIEE1, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1 New Known [69]
ENSG00000005001 PRSS22 BSSP-4, SP001LA, hBSSP-4 Known [70] Known [71]
ENSG00000005249 PRKAR2B PRKAR2, RII-BETA Known [72] Known [73]
ENSG00000005448 WDR54 - Known [74] New
ENSG00000006194 ZNF263 FPM315, ZSCAN44, ZKSCAN12 New New
ENSG00000006327 TNFRSF12A FN14, CD266, TWEAKR New Known [35]
ENSG00000006704 GTF2IRD1 BEN, WBS, GTF3, RBAP2, CREAM1, MUSTRD1, WBSCR11, WBSCR12, hMusTRD1alpha1 New known [36]
ENSG00000007392 LUC7L Luc7, SR+89, LUC7B1, hLuc7B1 New Known [75]
ENSG00000008300 CELSR3 FMI1, EGFL1, HFMI1, MEGF2, ADGRC3, CDHF11, RESDA1 New Known [76]
ENSG00000010539 ZNF200 - New New
ENSG00000010610 CD4 CD4mut Known [77] Known [78]
ENSG00000011143 MKS1 BBS13, FLJ20345, MKS, POC12 New New
ENSG00000011201 ANOS1 HH1, HHA, KAL, KMS, KAL1, ADMLX, WFDC19, KALIG-1 Known [44] Known [45]
ENSG00000011243 AKAP8L HAP95, NAKAP95 Known [79] Known [79]
ENSG00000011260 UTP18 WDR50, CGI-48 New Known [80]
ENSG00000012211 PRICKLE3 Pk3, LMO6 New New
ENSG00000013523 ANGEL1 Ccr4e, KIAA0759 New New
ENSG00000018236 CNTN1 F3, GP135, MYPCN Known [50] Known [51]
ENSG00000018280 SLC11A1 LSH, NRAMP, NRAMP1 Known [30] Known [52]
ENSG00000018625 ATP1A2 FHM2, MHP2 New Known [81]
ENSG00000023839 ABCC2 DJS, MRP2, cMRP, ABC30, CMOAT Known [82] Known [83]
ENSG00000025772 TOMM34 TOM34, URCC3, HTOM34P Known [84] Known [85]
ENSG00000029153 ARNTL2 CLIF, MOP9, BMAL2, PASD9, bHLHe6 Known [86] Known [87]
  1. The term “known” is assigned if the gene has been previously reported as differentially expressed in colorectal cancer (CRC) or in other types of cancer, otherwise “New” is used. The genes reported in common by OMICfpp with an orness value of 0.37 and 0.93, edgeR and DESeq2 are in bold entries