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Fig. 3 | BMC Genomics

Fig. 3

From: Human genes escaping X-inactivation revealed by single cell expression data

Fig. 3

Quantifying the iSNPs’ labels from 25 single cell lymphoblasts. a Each single cell is partitioned according to its tagged allelic iSNPs on ChrX, Chr17, and all autosomal chromosomes. The iSNPs are associated with maternal (pink), paternal (light blue) and balanced expression (gray). The cells are ordered from left to right according to their iSNP contributions (Additional file 1: Figure S4). On the right, the summary statistics of the Pool100 is shown. b A summary of the partition of iSNPs tags for all 25 single cells on ChrX, Chr17 and autosomal chromosomes. c A summary of the partition of iSNPs tags for Pool100. Blue and pink colors are associated with the paternal and maternal alleles, respectively. The striped pattern indicates biallelic iSNPs leaning towards paternal (blue) or maternal (pink) alleles. For single cells, the data is based on 375 iSNPs for ChrX, 808 iSNPs for Chr17 and 20,212 iSNPs for autosomal chromosomes. The data of Pool100 is based on 211 iSNPs for ChrX, 216 for Chr17 and 5360 iSNPs for autosomal chromosomes. For the source data see Additional file 5: Table S4

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