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Fig. 6 | BMC Genomics

Fig. 6

From: Human genes escaping X-inactivation revealed by single cell expression data

Fig. 6

LncRNAs assigned as escapees, and the groups of escapees according to their confidence level. a The dispersal of escapees along ChrX. Escapees belong to the lncRNAs and to the coding genes are indicated above and below the schematics of ChrX, respectively. b A table listing the 15 lncRNA escapee candidates. The orange color indicated escapee and the gray inactivated. An assignment that is based on a single iSNP is labeled with light orange. The white indicates lack of report or no expression. XIC, X inactivation center region. c Partition of the 75 genes that were mentioned as escapee candidates in this study. The categories are labeled ‘confirmed’, ‘approved’, ‘probable’ and ‘possible (see text). The two external resources that are used to define the groups are from the literature [13] and from single-cell by [16]. For a group of ‘probable’ escapee, we used escapee’s annotation from [10] as evidence. Note that 11 of the 15 listed lncRNA genes are included in the ‘possible’ escapee set. d A summary of the evidence-based groups for 75 genes. Genes are sorted according to the 4 evidence groups (as in c) The escapees are colored orange. Light orange indicates escapees that are supported by a single evidence from one cell only in fibroblasts. Inactivated genes are colored gray. White color indicates no expression or lack of report. The cell evidence is color coded showing support by one (light blue) or multiple cells (dark blue). Cases where evidence are based on Pool100 only are also marked light blue. PAR genes and lncRNAs are marked. Source data is in Additional file 6: Table S5

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