Human genes escaping X-inactivation revealed by single cell expression data

BMC Genomics

Table 1 Escapees from 101 primary single cell fibroblasts. A full list of all genes is available in Additional file 3: Table S4

Gene symbol	Gene type	# hSNPs per gene	Total iSNPs	# Cells with any observation	# Cells with biallelic observation^a	Biallelic iSNPs Ratio^b	Evidence poor^c
CD99	PAR	28	248	101	97	0.435
LAMP2		8	186	100	2	0.011
RBM3		7	110	100	3	0.027
ZFX		36	456	100	80	0.226
MTRNR2L10		10	699	98	80	0.200
LOC550643	ncRNA	5	99	94	2	0.020
SLC25A6	PAR	1	88	88	50	0.580
C1GALT1C1		5	246	85	2	0.012
SMC1A		2	66	64	18	0.288
DHRSX	PAR	60	134	63	12	0.097
FAM104B		17	937	63	2	0.002
TSPAN6		1	61	61	4	0.066
MAP 7D3		9	127	59	3	0.024
XIAP		24	97	56	1	0.031	*
HDHD1		19	186	49	8	0.091
DDX3X		9	99	41	6	0.091
CA5BP1	ncRNA	18	77	39	2	0.039
ZRSR2		11	42	34	6	0.143
RBM41		16	63	29	5	0.079
MST4		4	41	21	6	0.171
JPX	ncRNA	1	14	14	5	0.357
KLHL4		15	27	9	1	0.074	*
USP27X		1	4	4	2	0.500	*
RAB41		2	2	1	1	1.000	*

^aThe number of cells supporting the reported observations from all cells that have any observation
^bFraction of biallelically expressed iSNPs among all iSNPs associated with the gene, for example in USP27X there were overall 4 iSNPs, two of them were biallelic so the iSNPs ratio is 0.5
^cEvidence poor applies for < 10 iSNPs, or evidence based on one cell indicated by an asterisk

ISSN: 1471-2164