Table 1 Evaluation of genetic associations between RA and SCFAs (butyric acid, acetic acid, and propionic acid). RA-associated genes from three disease genetics resources (OMIM, the GWAS Catalog, and ClinVar) were used separately and combined
Disease Genetics | Recall | Mean Ranking (top %) | Median Ranking (top %) | P-value |
|---|---|---|---|---|
OMIM (15 RA genes) | 1.00 | 4.61 | 4.07 | 9.96E-4 |
GWAS (155 RA genes) | 1.00 | 4.33 | 2.44 | 0.0036 |
ClinVar (10 RA genes) | 1.00 | 4.61 | 4.07 | 9.96E-4 |
Combined (166 RA genes) | 1.00 | 3.52 | 2.44 | 0.0017 |