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Table 3 Evaluation of functional associations between RA and SCFAs (butyric acid, acetic acid, and propionic acid). RA-associated genes from three disease genetics resources (OMIM, the GWAS Catalog, and ClinVar) were used separately and combined

From: Data-driven multiple-level analysis of gut-microbiome-immune-joint interactions in rheumatoid arthritis

Disease Genetics

Recall

Mean Ranking (top %)

Median Ranking (top %)

P-value

OMIM (15 RA genes)

1.00

5.96

5.69

0.0023

GWAS (155 RA genes)

1.00

5.69

5.69

0.0018

ClinVar (10 RA genes)

1.00

5.69

5.69

0.0018

Combined (166 RA genes)

1.00

5.69

5.69

0.0018