Table 7 Evaluation of phenotypic associations between RA and SCFAs. RA-associated genes from three disease genetics resources (OMIM, the GWAS Catalog, and ClinVar) were used separately and combined
Disease Genetics | Recall | Mean Ranking (top %) | Median Ranking (top %) | P-value |
|---|---|---|---|---|
OMIM (15 RA genes) | 1.00 | 15.00 | 5.00 | 0.1022 |
GWAS (155 RA genes) | 1.00 | 23.33 | 7.50 | 0.2923 |
ClinVar (10 RA genes) | 1.00 | 14.72 | 5.00 | 0.0969 |
Combined (166 RA genes) | 1.00 | 16.94 | 5.83 | 0.1300 |