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Fig. 5 | BMC Genomics

Fig. 5

From: Proteome profiling of triple negative breast cancer cells overexpressing NOD1 and NOD2 receptors unveils molecular signatures of malignant cell proliferation

Fig. 5

Gene Ontology (GO) pathway enrichment analysis for identified differentially expressed proteins in NOD1 (HS578T/NOD1) (a) and NOD2 (HS578T/NOD2) (b) groups, generated by EnrichR (http://amp.pharm.mssm.edu/Enrichr) membership analysis, using the KEGG 2016 database. The length of the bar represents the statistical significance of the combined score in Fisher exact test for that specific gene-set or term. In addition, the brighter the color, the more significant that term is. Top supporting protein evidence for each GO cellular component term is presented at the left of horizontal bars. Heatmap (c) of GO enriched terms for identified differentially expressed proteins in HS578T/NOD1 and HS578T/NOD2 groups, generated in Metascape (http://metascape.org/gp), using KEGG, Reactome and GO databases. GO terms in heatmap are color coded from grey to brown according to log10(p) of the standard accumulative hypergeometric statistical test

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