Fig. 4

Schematic of the cliques and the corresponding gene expression levels in different cells. a Schematic of the cliques in different cell lines. a, b, and c represent a clique with three TFs. The Cyan, green, and magenta circles represent different cell lines. b Examples of shared cliques with seven TFs, Venn diagram of the number of overlapped regulated genes by the clique and gene expressions for these seven TFs in GM12878, K562, and MCF7 cells. c Clique and gene expression in K562, MCF7, and HUVEC cells. Clique with four TFs shared by K562, MCF7, and HUVEC cells. Venn diagram of the number of overlapped regulated genes by the clique in K562, MCF7, and HUVEC cells. The expression of the regulated genes by the clique in K562, MCF7, and HUVEC cells. d Two examples of cliques with RAD21, YY1, and TFAP2A and cliques with SIX5, NRF1, and TFAP2A shared by K562, GM12878, HUVEC, and MCF7. The shared TFs in cliques are colored blue, and the other TFs in cliques are colored orange. The expression levels of the shared TFs are labeled with the corresponding genes