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Table 1 Genes differentially expressed in ISIAH and WAG brain stems and referred to in Databases as associated with blood pressure regulation and hypertension

From: The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

Gene symbol Gene_ID log2
(fold_change) ISIAH/WAG
Gene definition
Rat Genome Database
Aoc3* 29473 −1.40 amine oxidase, copper containing 3 (vascular adhesion protein 1)
Cbs* 24250 0.54 cystathionine beta synthase
Chi3l1* 89824 −1.36 chitinase 3-like 1 (cartilage glycoprotein-39)
Col1a1* 29393 −0.73 collagen, type I, alpha 1
Col3a1* 84032 −1.08 collagen, type III, alpha 1
Cyp11a1* 29680 2.55 cytochrome P450, family 11, subfamily a, polypeptide 1
Cyp11b1 500892 1.12 cytochrome P450, family 11, subfamily b, polypeptide 1
Cyp11b2* 24294 1.12 cytochrome P450, family 11, subfamily b, polypeptide 2
Ephx2* # 65030 4.23 epoxide hydrolase 2, cytoplasmic
F2r* # 25439 0.81 coagulation factor II (thrombin) receptor
Fn1* 25661 −1.30 fibronectin 1
Gstm2* 24424 −1.10 glutathione S-transferase mu 2
Gucy1a3* 497757 −0.69 guanylate cyclase 1, soluble, alpha 3
Igfbp2* 25662 −0.51 insulin-like growth factor binding protein 2
Il18* # 29197 −1.29 interleukin 18
Npr1 24603 −0.61 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
Ptgds* 25526 −0.74 prostaglandin D2 synthase (brain)
Tlr3* 364594 0.96 toll-like receptor 3
DAVID
Acta2* 81633 −0.74 smooth muscle alpha-actin
Hba2 360504 0.58 hemoglobin alpha 2 chain
P2rx4* 29659 −0.88 purinergic receptor P2X, ligand-gated ion channel 4
Sult1a1* 83783 −0.85 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
  1. Genes associated with *- central nervous system diseases; # - brain ischemia;
  2. ISIAH and WAG – rat strains used in the study