Table 2 Genes differentially expressed in ISIAH and WAG brain stems and referred to in Rat Genome Database as associated with central nervous system diseases

Abcg2

ATP-binding cassette, subfamily G (WHITE), member 2

Acadsb

acyl-CoA dehydrogenase, short/branched chain

Acta2

smooth muscle alpha-actin

Aldh1a1

aldehyde dehydrogenase 1 family, member A1

Aldh1a2

aldehyde dehydrogenase 1 family, member A2

Aoc3

amine oxidase, copper containing 3 (vascular adhesion protein 1)

Atp10a

ATPase, class V, type 10A

Bmp6 ^#

bone morphogenetic protein 6

Cadps2

Ca++ − dependent secretion activator 2

Car8

carbonic anhydrase 8

Casp4

caspase 4, apoptosis-related cysteine peptidase

Cbs

cystathionine beta synthase

Cckbr

cholecystokinin B receptor

Chi3l1

chitinase 3-like 1 (cartilage glycoprotein-39)

Col1a1

collagen, type I, alpha 1

Col3a1

collagen, type III, alpha 1

Col6a3

procollagen, type VI, alpha 3

Cyp11a1

cytochrome P450, family 11, subfamily a, polypeptide 1

Cyp11b2

cytochrome P450, family 11, subfamily b, polypeptide 2

Des

desmin

Eif3c

eukaryotic translation initiation factor 3, subunit C

Ephx2 ^#

epoxide hydrolase 2, cytoplasmic

Ercc2

excision repair cross-complementing rodent repair deficiency, complementation group 2

F2r ^#

coagulation factor II (thrombin) receptor

Fhit

fragile histidine triad gene

Flna

filamin A, alpha

Fn1

fibronectin 1

Gabra6 ^#

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Gabrd

gamma-aminobutyric acid (GABA) A receptor, delta

Grm2

glutamate receptor, metabotropic 2

Gstm2

glutathione S-transferase mu 2

Gucy1a3

guanylate cyclase 1, soluble, alpha 3

Hoxb8

homeo box B8

Igf2 ^#

insulin-like growth factor 2

Igfbp2

insulin-like growth factor binding protein 2

Il16

interleukin 16

Il18 ^#

interleukin 18

Itpr1

inositol 1,4,5-trisphosphate receptor, type 1

Itpripl1

inositol 1,4,5-trisphosphate receptor interacting protein-like 1

Ltbp1 ^#

latent transforming growth factor beta binding protein 1

Mal

mal, T-cell differentiation protein

Mapre2

microtubule-associated protein RP/EB family member 2-like

Mccc2

methylcrotonoyl-CoA carboxylase 2 (beta)

Mcm7

minichromosome maintenance complex component 7

Mgmt

O-6-methylguanine-DNA methyltransferase

Myh11

myosin, heavy chain 11, smooth muscle

Ncaph

non-SMC condensin I complex, subunit H

Nptx2

neuronal pentraxin II

P2rx4

purinergic receptor P2X, ligand-gated ion channel 4

P2ry12

purinergic receptor P2Y, G-protein coupled, 12

Pld5

phospholipase D family, member 5

Ppm1k

protein phosphatase, Mg2+/Mn2+ dependent, 1 K

Ptgds

prostaglandin D2 synthase (brain)

Rbp4

retinol binding protein 4, plasma

Retsat

retinol saturase (all trans retinol 13,14 reductase)

Snx14

sorting nexin 14

Sult1a1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

Tlr3

toll-like receptor 3

Ttr ^#

transthyretin

Vtn

vitronectin

Zbtb16

zinc finger and BTB domain containing 16