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Fig. 2 | BMC Genomics

Fig. 2

From: Enrichment post-library preparation enhances the sensitivity of high-throughput sequencing-based detection and characterization of viruses from complex samples

Fig. 2

Discrimination of ZIKV, CHIKV, and DENV in mock clinical samples at clinically relevant titers. Sequencing libraries made from serum samples spiked with ZIKV, DENV-2 and CHIKV were prepared in duplicate and either probed singly or within pools of four or 12. a The percentage of pathogen-specific reads detected within the synthetic co-infection samples is shown, along with the standard error of the mean for the two replicates. b-d Coverage plots demonstrating the number of reads that mapped to ZIKV, CHIKV, and DENV, respectively, as well as the distribution of those reads along the length of each genome

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