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Table 4 Pathway analysis for differentially methylated genes between intestinal mucosa and saliva samples

From: Comparing DNA methylation profiles in saliva and intestinal mucosa

  Pathway Count P value Benjamini P values
hsa04371 Apelin signalling pathway 5/137 p < 0.001 0.01
hsa04810 Regulation of actin cytoskeleton 6/211 p < 0.001 0.01
hsa05202 Transcriptional misregulation in cancer 6/174 p < 0.001 0.01
hsa01100 Metabolic pathways 11/1241 p < 0.001 0.01
hsa04022 cGMP-PKG signalling pathway 5/162 p < 0.001 0.01
hsa04070 Phosphatidylinositol signalling system 4/97 p < 0.001 0.01
hsa04144 Endocytosis 6/257 p < 0.001 0.01
hsa04666 Fc gamma R-mediated phagocytosis 4/90 p < 0.001 0.01
hsa04621 NOD-like receptor signalling pathway 4/158 p < 0.001 0.01
hsa04020 Calcium signalling pathway 5/180 p < 0.001 0.01
hsa04915 Estrogen signalling pathway 4/98 p < 0.001 0.02
hsa04724 Glutamatergic synapse 4/114 p = 0.001 0.03
hsa04662 B cell receptor signalling pathway 3/70 p = 0.001 0.03
hsa05132 Salmonella infection 3/85 p = 0.001 0.03
hsa04062 Chemokine signalling pathway 4/182 p = 0.002 0.04
hsa04921 Oxytocin signalling pathway 4/152 p = 0.002 0.04
  1. P value based on number of differentially expressed genes
  2. Count is the number of genes within the test set over the total of number of genes within the GO term