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Table 2 Genomic regions associated with milk fatty acid traits in the multi-population analysis and suggested candidate genes

From: Multi-population GWAS and enrichment analyses reveal novel genomic regions and promising candidate genes underlying bovine milk fatty acid composition

Regiona Start (Mbp) End (Mbp) Traits associated (and % of explained genetic variance) Candidate genes
1a 19.92 19.93 C16:0(3.1)  
1b 101.0 101.0 C18 index(2.8)  
1c 141.3 142.5 C15:0(3.9)  
2a 12.5 19.8 C8:0(3.7), C10:0(3.0) OSBPL6, AGPS
2b 54.9 59.8 C14:1(1.6), C16:0(3.6), C16:1(2.1), C14 index(1.5)  
2c 64.1 67.8 C16:1(2.3), C16 index(2.3)  
2d 106.5 135.6 C12:0(2.5), C15:0(5.6), C16:0(2.8), C18:1c9(3.8) MOGAT1, FABP3, MECR
3 116.2 119.4 C18:3n3(4.3), CLA(3.2) PRLH
4 15.59 15.6 C15:0(5.2)  
5a 10.33 10.36 C15:0(9.0)  
5b 65.7 82.8 C8:0(3.9), C10:0(2.5) CHPT1
5c 87.4 99.0 C8:0(4.3), C10:0(3.2), C12:0(2.6), C14:1(1.7), C16:0(2.7), C16:1(2.1), C18:1c9(5.6), CLA(3.2), C14 index(2.4), C16 index(4.9) MGST1, PLBD1, LRP6
6 41.4 41.4 C18 index(2.9)  
7a 14.6 15.5 C8:0(3.3), C10:0(2.2)  
7b 78.4 78.4 C18:2n6(3.3)  
7c 81.6 83.2 C12:0(3.0), C15:0(6.0)  
8a 57.5 59.7 C15:0(6.1), C16:1(2.0), C16 index(2.5) PIGO, STOML2
8b 79.9 98.4 C14:0(3.9), C18:0(4.1), CLA(3.3)  
9a 25.5 25.6 C14:1(1.7)  
9b 81.3 81.3 C15:0(5.0)  
10a 1.1 8.6 C10:0(2.0), C12:0(3.5)  
10b 12.9 12.9 C14:1(1.6), C18:0(3.6) SLC51B
10c 78.1 80.1 C18:3n3(4.9) PIGH
10d 87.5 93.1 C18:0(4.1), CLA(3.4), C18 index(2.5)  
11a 24.7 26.7 C16:0(2.6) ABCG5, ABCG8
11b 58.81 58.89 C16:0(2.8)  
12a 17.1 17.1 C18:1c9(3.5)  
12b 24.0 24.8 C14:1(1.8) ALG5
12c 70.0 77.4 CLA(3.5), C16 index(2.5)  
13 64.6 65.7 C10:0(2.4) ACSS2
14a 1.5 5 C8:0(7.8), C10:0(3.6), C14:0(8.8), C14:1(2.1), C15:0(16.3), C16:0(33.8), C16:1(7.8), C18:1c9(34.1), C18:2n6(34.3), C18:3n3(24.2), CLA(14.6), C14 index(4.5), C16 index(11.3), C18 index(11.4) DGAT1, GPAA1
14b 5.2 20 C8:0(4.3), C10:0(2.7), C15:0(5.2), C16:0(11.2), C16:1(6.6), C18:1c9(10.5), C18:2n6(15.2), C18:3n3(12.8), CLA(4.7), C14 index(1.8), C16 index(3.4), C18 index(4.4) ST3GAL1
14c 44.7 49.9 C14:1(2.0), C16:1(1.9), C14 index(1.6), C18 index(2.7) PMP2, FABP9, FABP4 FABP12
15a 27.2 31.2 C10:0(2.3), C14:0(4.6), C18:0(4.6) APOA1, APOA4, APOA5, DPAGT1
15b 46.9 65.9 C10:0(2.8) CAT
16a 23.8 25.22 C18:0(3.8), C16 index(2.3)  
16b 57.53 57.58 C16:1(1.7), C16 index(2.1)  
17a 17.4 22.6 C16:1(3.0), C16 index(2.1) MGST2
17b 27.8 44.1 C8:0(5.9), C10:0(3.0), C16:1(2.6), C18:3n3(4.8), C16 index(2.3) LARP1B
19 37.3 61.3 C8:0(7.6), C10:0(12.6), C12:0(13.6), C14:0(22.3), C16:0(4.6), C18:1c9(3.9), C14 index(3.1), C18 index(2.5) ACLY, BRCA1, FASN, STAT5A,
20a 32.4 34.2 C16:1(1.9), C18:0(4.3) PRKAA1
20b 36.7 36.9 C14:1(1.6), C18:1c9(3.9)  
20c 55.3 60.4 C14 index(1.6), C18 index(2.8)  
21 53.8 59.1 C10:0(2.3), C12:0(2.9), C14:0(3.3), C18:1c9(4.1)  
22 59.12 59.13 C14 index(1.6)  
23a 26.7 32.7 CLA(4.3) AGPAT1, ATAT1
23b 33.5 36.5 C15:0(5.8)  
23c 40.7 43.5 C18:1c9(3.4), C16 index(2.1), C18 index(2.6)  
24 10.2 10.2 C18:0(4.2)  
25a 9.8 9.9 C12:0(3.1)  
25b 24.7 24.7 C18:1c9(3.5)  
25c 41.4 41.7 CLA(3.0) C14 index(1.4)  
26 2.9 43.0 C8:0(3.7), C10:0(5.5), C12:0(3.3), C14:0(8.0), C14:1(39.0), C16:0(2.4), C16:1(13.6), C18:0(4.5), C14 index(45.3), C16 index(19.7), C18 index(3.3) SCD, ELOVL3, ACSL5, GPAM
27 37.0 42.2 C16:0(2.9)  
28 36.6 37.2 C16:1(2.3), C16 index(2.5)  
29 32.9 40.5 C16:0(2.5), C18:1c9(3.2) TKFC
  1. aBTA number with subscript of alphabets to denote the multiple regions within a chromosome