Fig. 2
Genetic diversity within and between parental populations used in the genetic cross. a. The 279 Mbp V3 genome assembly of H. contortus consists of five autosomal and two X chromosome scaffolds, named based on synteny with Caenorhabditis elegans chromosomes. The size of each scaffold is indicated, and are presented in order by length (Mbp). b. Geographic origin of the susceptible MHco3(ISE) and ivermectin resistant MHco10(CAVR) and MHco4(WRS) populations used in the genetic crosses. All populations are archived at the Moredun Research Institute, UK – while MHco3(ISE) has been maintained there for decades, it was originally isolated in East Africa. c. Within-population nucleotide diversity for each of the parental populations, calculated as mean diversity per 100 kbp windows throughout the genome using npstat. d. Between population diversity, calculated as pairwise FST in 10 kbp windows throughout the genome using popoolation2. Colours here and throughout represent the chromosomal scaffolds as described in A